Postdoctoral Research Associate - Hematology

St. Jude Children’s Research Hospital is seeking a Postdoctoral Research Associate for the Cheng Laboratory. The role focuses on developing and applying bioinformatics, computational genomics, and machine-learning methods for functional genomics, genome engineering, and personalized genome-editing therapies.

Responsibilities:

• Developing machine-learning and deep-learning models to predict genome-editing activity, specificity, and off-target effects
• Integrating genomic sequence with high-throughput biochemical, cellular, and functional genomic data
• Developing computational methods for analysis and interpretation of genome-editing and functional genomic datasets
• Applying modern ML approaches to understand the effects of genetic variation and improve genome-engineering strategies
• Working closely with experimental collaborators to design, evaluate, and validate computational models