Senior Director, Head Operational Excellence, Global Clinical Operations

Role Overview

• Build and Lead the OpEx Function
• Establish the OpEx vision, operating model, organizational structure and multi-year road map
• Build and mentor a high performing operational excellence team capable of driving enterprise transformation
• Partner with EPIX functional leads to embed operational discipline across the clinical lifecycle and GCO
• Standardize Operating Models
• Assess current operating models, map E2E processes to gain efficiency and speed.
• Design harmonized, scalable processes and frameworks for planning, forecasting, feasibility, budgeting, execution, enrollment management and closeout.
• Develop governance structures that drive consistency and eliminate operational variability across functions and geographies
• Lead "way of working" harmonization across Innovative and Generics portfolios
• Own Metrics and KPI Governance
• Define and maintain the metrics performance aligning KPI's to quality timelines, predictability, vendor performance, patient/site experience, and cost
• In collaboration with a partner organization, design dashboards and performance reviews that inform decisions at study/ functional/portfolio levels
• Collaborate with other functional areas to establish governance and steering committees
• Ensure metrics are actionable, driving accountability escalation and performance improvement
• Lead Enterprise Level Operational Initiatives
• Champion continuous improvement across planning, execution, governance, and vendor management
• Drive adoption of new processes systems tools and behaviors through structured change management and training
• Shape operational decision-making frameworks that support portfolio level prioritization and resource allocation
• Drive process simplification and implement technology enhancements to optimize speed, accuracy, and efficiency.
• Ensure Organizational Readiness and Scalability
• Define readiness criteria for key study milestones and ensure teams are equipped to meet them
• Build operating structures that support portfolio expansion new modalities and increasing trial complexity
• Align operational excellence strategies with technology, digital and AI/ML teams to maximize adoption and impact
• Oversee resource allocation and governance for GCO

Requirements

• Bachelor's Degree required
• Advanced degree in a scientific, engineering, or supply chain discipline preferred
• 12+ years in Clinical Operations, Operational Excellence, R&D Strategy, or related transformation roles
• Proven success designing and implementing enterprise-level operating models, governance frameworks, and performance systems.
• Demonstrated ability to drive measurable cycle-time, quality, and efficiency improvements.
• Strong analytical capability with fluency in KPIs, metrics-driven decision making, and operational dashboards.
• Track record of influencing senior leaders and driving adoption in a complex, global matrix environment.
• Experience leading high performing teams and large-scale operational change.
• Willingness and ability to routinely travel domestically and abroad.
• Experience in both large/established pharma and smaller/mid-sized pharma where there is transformational or high growth environments.
• Familiarity with predictive analytics, digital enablement AI/ML applications and scenario modeling experience.
• Lean Six Sigma or advanced continuous improvement certification.

Benefits

• Comprehensive Health Insurance: Medical, Dental, Vision, and Prescription coverage starting on the first day of employment, providing the employee enrolls.
• Retirement Savings: 401(k) with employer match, up to 6% and an annual 3.75% Defined Contribution to the 401k plan.
• Time Off: Paid Time Off including vacation, sick/safe time, caretaker time, and holiday.
• Life and Disability Protection: Company paid Life and Disability insurance.
• Additional benefits include, but are not limited to, Employee Assistance Program, Employee Stock Purchase Plan, Tuition Assistance, Flexible Spending Accounts, Health Savings Account, Life Style Spending Account, Volunteer Time Off, Paid Parental Leave, if eligible , Family Building Benefits, Virtual Physical Therapy, Accident, Critical Illness and Hospital Indemnity Insurances, Identity Theft Protection, Legal Plan, Voluntary Life Insurance and Long Term Disability and more.