Senior Clinical Project Manager

Deciphera Pharmaceuticals is seeking a Senior Clinical Project Manager to lead the execution of complex global clinical studies. The role oversees study teams and external partners, manages timelines and budgets, and ensures trials are conducted with quality and in compliance with applicable requirements.

Responsibilities:

• Lead the planning, execution, and delivery of assigned global clinical studies, with responsibility for timelines, budgets, quality, and overall operational execution
• Identify and address operational risks and challenges to keep studies on track
• Lead cross-functional study teams, driving collaboration, accountability, decision-making, and problem-solving
• Partner across Clinical Operations, Data Management, Regulatory, Clinical Supply, and other functions to support global study execution
• Oversee CROs and external vendors, monitoring performance and ensuring alignment with study timelines, budgets, quality expectations, and contractual obligations
• Communicate study progress, risks, and key decisions clearly to internal stakeholders and Clinical Operations leadership
• Contribute to Clinical Operations processes and ways of working that support efficient, high-quality study execution
• Other duties and responsibilities as assigned

Requirements:

• Bachelor's degree in health science or a related field and 8+ years of clinical research experience, including meaningful responsibility for managing complex clinical trials
• Strong global clinical trial and later-stage development experience, ideally including Phase III
• Candidates with substantial experience leading large, complex Phase II studies will also be considered
• Demonstrated ability to lead and influence cross-functional study teams
• Hands-on experience managing CROs and vendors and proactively addressing operational risks
• Strong working knowledge of GCP, ICH, FDA, and applicable global clinical trial requirements
• Strong communication and problem-solving skills, with the ability to work independently, advocate for what is needed, and recognize when to engage others for support
• Phase III global study experience
• Oncology or rare disease clinical development experience
• Experience with eTMF, EDC, IWRS, and RBQM platforms
• Experience managing clinical study budgets and contracts
• Experience within a fast-paced biotechnology environment
• PMP certification or equivalent project management training