Key skills
Machine learning engineeringAI engineeringData engineeringCloud engineeringLLMsRetrieval-augmented generationEmbeddingsVector databasesAgentic workflowsAI evaluation methodsAWS CloudData pipelinesIntegration architectureContainersCI/CDSecure development practicesPythonVersion controlModular designTestingAIMachine LearningAgenticData EngineeringAWSVersion ControlLeadershipMentoringCommunication
About this role
Amgen is a leading biotechnology company focused on serving patients living with serious illnesses. They are seeking a Senior Machine Learning Engineer to build scalable AI proofs-of-concept and collaborate with product managers and business stakeholders to translate business needs into practical AI solutions.
Responsibilities:
- Build scalable AI proof-of-concepts that are designed to demonstrate a clear path from prototype to enterprise-scale solution
- Partner with product managers, business stakeholders, platform teams, and AI & software engineers to translate ambiguous business needs into practical AI solutions with measurable value
- Design and implement modern AI systems using LLMs, agentic workflows, retrieval-augmented generation, data pipelines, APIs, cloud-native services, and enterprise platforms
- Rapidly validate feasibility and value by assessing technical risk, data readiness, integration complexity, user experience, security considerations, performance, cost, and business impact
- Create reusable technical assets such as reference architectures, reusable components, documentation, decision records, and handoff materials that enable product, platform, or delivery teams to scale successful POCs
- Raise the technical bar for the team by modeling strong engineering practices, mentoring others, improving delivery patterns, and bringing clear ownership and accountability to uncertain, fast-moving work
Requirements:
- Doctorate degree
- Master's degree and 2 years of relevant experience
- Bachelor's degree and 4 years of relevant experience
- Associate's degree and 8 years of relevant experience
- High school diploma / GED and 10 years of relevant experience
- 4-6 years of relevant experience in AI engineering, machine learning engineering, software engineering, data engineering, cloud engineering, or related technical roles
- Demonstrated experience building full-stack AI-powered applications that move beyond experimentation and are designed with scalability, security, evaluation, and maintainability in mind
- Strong understanding of modern AI application architecture, including LLMs, retrieval-augmented generation, embeddings, vector databases, agentic workflows, tool use, orchestration frameworks, and AI evaluation methods
- Experience defining and applying evaluation methods for AI solutions, including accuracy, reliability, hallucination risk, latency, usability, safety, cost, and fitness for intended use
- Ability to translate ambiguous business problems into practical technical approaches, make sound tradeoffs, and rapidly validate feasibility, value, risks, and path to scale
- Experience with AWS Cloud, data pipelines, integration architecture, containers, CI/CD, observability, and secure development practices
- Strong software engineering foundation, preferably with Python and modern development practices, including testing, version control, modular design, documentation, and maintainable code
- Demonstrated ability to responsibly use AI tools to improve engineering productivity, explore technical solutions, automate repetitive tasks, and enhance the delivery of machine learning or software products
- Excellent communication, ownership, and cross-functional leadership skills, with the ability to partner effectively with product managers, business stakeholders, platform teams, and AI and software engineers