Project Manager (CMC / Development Operations)

Epicrispr Biotechnologies is an early-stage biotechnology company developing a novel technology platform for gene regulation. They are seeking a highly organized and proactive Project Manager to support execution of CMC and cross-functional development programs, focusing on managing manufacturing activities and broader product development initiatives.

Responsibilities:

• Oversee execution of manufacturing runs at Contract Manufacturing Organizations (CMOs) for lead programs, including tracking completion of action items, monitoring program activities and milestones, and driving resolution of risks and issues across the cross-functional team
• Serve as key alliance manager for CMC vendors in partnership with the VP of Tech Ops, ensuring effective collaboration and execution across external partners
• Track and maintain visibility of program timelines, dependencies, and deliverables across CMC and broader development workstreams using appropriate tracking tools
• Organize, schedule, and facilitate internal cross-functional program meetings to ensure alignment and clear communication across teams
• Maintain, organize, and continuously improve program documentation, trackers, and repositories (e.g., Smartsheet, SharePoint)
• Document key decisions, risks, assumptions, issues, action items, and overall program plans in a clear and structured manner
• Provide clear, timely communication of program status updates, risks, and key decisions to leadership and relevant stakeholders
• Coordinate across CMC, Clinical, Regulatory, and Nonclinical teams to ensure alignment and execution of integrated program deliverables
• Support planning and coordination of key nonclinical and regulatory milestones as needed to enable program execution
• Partner with the Associate Director to identify, develop, and implement opportunities to streamline and standardize project management processes, tools, and workflows across Epicrispr
• Help build scalable project management infrastructure that improves visibility, accountability, and execution discipline across programs and teams

Requirements:

• Bachelor's degree required; Master's degree preferred
• 3–7+ years of experience in project or program management within biotechnology, pharmaceutical, or life sciences environments
• Strong experience in CMC, manufacturing, or technical operations preferred
• Proficiency with project tracking tools such as Smartsheet and SharePoint
• Strong organizational, communication, and documentation skills
• Ability to manage multiple priorities in a fast-paced, dynamic environment
• Strong attention to detail and commitment to follow-through and accountability
• Comfortable working in ambiguous, early-stage biotech environments
• Strong interpersonal skills with the ability to collaborate across technical and non-technical teams
• Ability to manage conflict and remain composed under pressure
• Experience in startup or rapidly scaling biotech environments is a plus