Director, Head of Product Management – AI-Enabled Precision Medicine (Therapeutics & Innovations)

Natera is redefining the future of precision medicine by integrating AI with healthcare to create next-generation treatment modalities. The Director, Head of Product Management will lead product strategy and execution for the AI-enabled therapeutics platform, ensuring alignment with business goals and market needs.

Responsibilities:

• Define and own the product vision and roadmap for AI-enabled tools for precision medicine offerings (e.g., biomarkers, trial enablement tools, co-development platforms) via genomic language models, biomedical AI agents, AI-driven analysis platforms, forecasting algorithms
• Identify high-value use cases across drug development (e.g., trial design, patient selection, translational insights, companion diagnostics)
• Translate platform capabilities into clear product strategies aligned with business goals
• Lead the end-to-end product lifecycle: concept → validation → build → launch → iteration
• Partner with R&D, data science, and engineering to define product requirements and ensure high-quality execution
• Drive prioritization decisions across competing opportunities based on impact, feasibility, and strategic alignment
• Engage with biopharma partners, clinicians, and internal stakeholders to deeply understand needs and workflows
• Synthesize customer insights into product requirements and roadmap decisions
• Continuously assess market trends, competitive landscape, and emerging technologies
• Serve as the central hub across Product, R&D, Clinical, BD, and Marketing
• Align stakeholders around a unified product strategy and execution plan
• Drive decision-making in a matrixed, fast-moving environment
• Partner with commercial and BD teams to define product positioning, packaging, and pricing
• Support go-to-market strategy, including pilot programs, partnerships, and scaled deployments
• Ensure successful product launches with clear value propositions and supporting evidence
• Define requirements for product validation, including analytical, clinical, and real-world evidence
• Ensure products meet scientific, regulatory, and commercial expectations
• Partner with clinical and regulatory teams to align product strategy with approval pathways where applicable
• Build and mentor a high-performing product management function
• Establish product processes, operating cadence, and best practices
• Foster a culture of ownership, speed, and scientific rigor

Requirements:

• 8–12+ years of experience in product management, product strategy, or related roles in biotech, life sciences, or healthcare technology
• Proven track record of building and launching complex, data-driven products
• Strong understanding of drug development workflows and/or clinical diagnostics
• Exceptional ability to translate complex science into clear product decisions and strategies
• Demonstrated success leading cross-functional teams in ambiguous environments
• Strong commercial acumen, including product-market fit, pricing, and partnership models
• Advanced degree (PhD, MD, MS, or equivalent) in life sciences, bioengineering, computational biology, or related field preferred
• Experience working with AI/ML-driven products or data platforms is highly preferred
• Experience with biomarker development, oncology, or precision medicine
• Background in diagnostics + therapeutics integration
• Experience in early-stage or high-growth environments