Senior Director, Internal Medicine Portfolio Strategy Lead

Role Overview

• Lead development of long-range commercial and portfolio strategy across the Internal Medicine and Antivirals portfolio
• Establish integrated near-, mid-, and long-term views of portfolio opportunities, risks, and investment priorities to inform enterprise decision-making
• Synthesize scientific, clinical, commercial, access, competitive, financial, and patient insights to identify priority opportunities and strategic trade-offs
• Monitor shifts in the scientific, competitive, and market landscape to identify emerging trends, discontinuities, and implications for future Internal Medicine and Antivirals strategy
• Translate portfolio strategy into clear recommendations, implications, and decision materials for leadership, governance forums, and cross-functional portfolio discussions
• Provide senior commercial strategy leadership for portfolio prioritization, investment choices, and development opportunities across Internal Medicine and Antivirals priorities
• Pressure-test commercial assumptions, value drivers, risks, uncertainties, resource implications, and evidence needs that may influence future launch potential, lifecycle value, and portfolio performance
• Lead development of executive-ready materials that communicate strategic rationale, opportunity attractiveness, trade-offs, scenarios, and recommended actions
• Partner with cross-functional leaders to align on key choices related to portfolio sequencing, indication prioritization, evidence generation, market development, and lifecycle opportunities
• Oversee early commercial assessments for pipeline assets, mechanisms, indications, disease-area opportunities, and potential future product concepts across Internal Medicine and Antivirals
• Guide assessment of strategic fit, market potential, valuation inputs, competitive scenarios, portfolio implications, and prioritization considerations for potential external opportunities
• Provide senior matrix leadership across cross-functional partners, helping align priorities, clarify decision points, and strengthen high-quality strategic outputs.

Requirements

• Applicant must have a bachelor's degree with at least 12 years of experience; OR a master's degree with at least 10 years of experience; OR a PhD with 7+ years of experience
• Experience in pharmaceutical, biotechnology, life sciences, commercial development, portfolio strategy, corporate strategy, business development, forecasting, market research, analytics, or related field
• Demonstrated experience leading complex cross-functional initiatives, influencing in matrixed environments, and shaping senior-level portfolio or investment decisions without direct authority
• Strong strategic and analytical skills, with ability to synthesize complex scientific, clinical, market, access, and competitive information into clear recommendations
• Experience leading portfolio strategy, early commercial assessment, business case development, opportunity assessment, investment prioritization, or cross-functional strategic planning
• Ability to engage in scientific and clinical dialogue and translate implications for commercial opportunity, differentiation, portfolio value, and enterprise decision-making
• Strong communication, executive presence, problem-solving, and stakeholder management skills.

Benefits

• 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
• Paid vacation
• Holiday and personal days
• Paid caregiver/parental and medical leave
• Health benefits to include medical, prescription drug, dental and vision coverage