Senior Principal Scientist, Tech Ops – CMC Science

Role Overview

• Acts as a subject matter expert in recombinant process science, providing advanced technical knowledge to support complex product-related activities.
• Leads defined technical workstreams or projects within broader product initiatives.
• Delivers high-quality scientific outcomes in line with project objectives, timelines, and performance expectations.
• Contributes technical input to the development and refinement of the product technical roadmap.
• Identifies and evaluates improvement opportunities (e.g., process robustness, yield, compliance) and supports their assessment and implementation.
• Provides scientific input into business cases and supports data-driven decision-making processes.
• Works within a global, matrixed IPT environment, collaborating with Manufacturing, MS&T, Quality, and Regulatory functions.
• Ensures application of sound scientific principles and compliance in product lifecycle activities, including process changes and technology transfers.
• Provides input to technical decision-making processes, including change controls, validation strategies, and lifecycle management activities.
• Supports data analysis, process understanding, and technical risk assessments.
• Contributes to the identification and implementation of process improvements and efficiency gains.
• Applies scientific methodologies and data analysis to improve process consistency and product quality.
• Supports implementation of best practices and innovative approaches within the IPT.
• Communicates complex technical information clearly to cross-functional stakeholders.
• Contributes to technical discussions and governance forums as required.
• Builds effective working relationships to support delivery of product objectives.
• Provides guidance and informal mentoring to junior scientists and team members.

Requirements

• PhD in Biochemistry, Biotechnology, Chemical Engineering, or related Life Sciences discipline.
• Typically 8–12 years of relevant experience in biopharmaceutical development and/or manufacturing within a GMP environment.
• Strong expertise in recombinant product process development, manufacturing, and lifecycle management.
• Experience contributing to complex technical projects in a matrix environment.
• Solid understanding of process validation, technology transfer, and regulatory requirements.
• Demonstrates strong project management skills, including planning, coordination, and execution of multiple projects to ensure timely delivery of objectives.

Benefits

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